When Depression Hasn't Responded,
It Can Be Tough To Keep Going…

Depression Treatment Shouldn't Be
One-Size-Fits-All

  • Treatment-resistant depression is more than having a bad day or going through a difficult season. It can affect your energy, motivation, relationships, work, sleep, concentration, and ability to enjoy the life around you.

    And when you've already tried multiple treatments without enough improvement, hearing “let's just try another medication” can be discouraging.

    We take a different approach.

  • Ketamine or SPRAVATO isn't appropriate for everyone.

    That's why the first step isn't treatment.

    It's a conversation.

    We'll review what you've tried, what hasn't worked, your medical and psychiatric history, your current medications, potential risks, and your goals. Then we'll discuss whether SPRAVATO®, ketamine-based treatment, another treatment approach, or coordination with another specialist makes the most sense.

  • When you've already tried multiple treatments for depression without enough improvement, another prescription isn't the real goal.

    Getting your life back is.

    Successful treatment of treatment-resistant depression isn't only about improving a number on a depression questionnaire. It's about creating meaningful change in the parts of life depression has taken away.

    That may mean:

    • Having the energy to get through the day

    • Feeling interested in people and activities again

    • Thinking and concentrating more clearly

    • Being more present with family and friends

    • Returning to work, responsibilities, and routines

    • Feeling that treatment is finally moving in the right direction

    No treatment works for everyone, and neither ketamine nor SPRAVATO® can guarantee remission. That's why we evaluate your response rather than simply continuing treatment by default.

    The goal isn't to keep treating depression. The goal is to find a treatment that meaningfully changes how you're living with it.

SPRAVATO® or Ketamine for Treatment-Resistant Depression

SPRAVATO® is the brand name for esketamine, a prescription nasal medication used to treat treatment-resistant depression in adults.

Unlike traditional antidepressants that primarily target serotonin, norepinephrine, or dopamine pathways, esketamine acts through the brain's NMDA/glutamate system, providing another treatment approach for appropriate patients who haven't received adequate benefit from previous antidepressant treatment.

SPRAVATO isn't taken home. Treatment occurs in a medically supervised setting where you can be monitored before, during, and after treatment.

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Ketamine has also been studied as a treatment for difficult-to-treat depression. Its use for depression is off-label, meaning ketamine itself is FDA-approved as an anesthetic but is not FDA-approved specifically to treat depression.

For carefully selected patients, we may discuss ketamine as one of several potential options. We believe these treatments deserve the same careful medical evaluation as any other significant therapy—not a one-size-fits-all protocol or a promise of a miracle cure.

Who We Are

  • Errin Weisman, DO provides thorough, approachable care for patients with complex concerns who need more time, better access, and a physician who sees the whole picture.

    Before recommending treatment, we take the time to understand your diagnosis, previous treatments, medications, medical history, physical health, and what you want your life to look like—not simply your depression score.

  • Advanced treatment. Close to home.

    Patients in rural communities shouldn't necessarily have to travel to a major metropolitan medical center to explore contemporary treatment options.

    Weisman Medical Services brings evidence-based, innovative care to Southwestern Indiana while preserving something increasingly difficult to find in medicine: a physician who has time to listen.

    We treat the person—not just the depression.

    Depression doesn't occur in isolation. Sleep, hormones, chronic illness, medications, substance use, anxiety, trauma, physical health, relationships, and other factors can all influence how someone feels.

    Our goal is to understand the bigger picture before deciding what treatment makes sense.

    A physician-led experience.

    You aren't simply coming to our office for a treatment session. Your care begins with a medical evaluation and continues with monitoring, follow-up, and reassessment of whether treatment is actually helping you.

  • At Weisman Medical Services, we believe exceptional healthcare begins with listening, understanding, and treating the whole person.

    Thorough Care — We take the time to understand your symptoms, history, previous treatments, and goals—not just the reason listed on your appointment.

    Approachable Medicine — You deserve a physician who listens without judgment, explains your options clearly, and makes it comfortable to ask questions.

    Evidence-Based Innovation — We bring contemporary treatment options and evidence-based medicine to rural Southwestern Indiana while remaining thoughtful about what is appropriate for each patient.

    Whole-Person Care — Mental health, physical health, hormones, chronic illness, medications, relationships, and everyday life are interconnected. We look at the bigger picture.

    Better Access — Through in-office care, telemedicine, home visits, and specialized services, we work to make high-quality medical care easier to access.

    Individualized Treatment — Medicine isn't one-size-fits-all. We focus on finding the right approach for the person in front of us.

Let’s Work Together

You’ve already taken an important step by looking for a different approach to your depression. The next step is simply starting the conversation.

At Weisman Medical Services, we’ll take the time to learn your story, understand what you’ve already tried, and determine whether SPRAVATO®, ketamine-based treatment, or another approach may be appropriate for you.

You don’t have to figure out the next step on your own.

Complete our secure online form and our team will contact you, or call or text our office (812) 441-4290 to get started.

Have questions before scheduling? That’s okay, too. Reach out at (812) 441-4290 or hello@weismanmedicalservices.com and let us help you understand the process.

Let’s work together to find a path forward.